Preliminary Results of a Phase I / II Study of Simultaneous Boost Irradiation Radiotherapy for Locally Advanced Nasopharyngeal Carcinoma
نویسنده
چکیده
Nasopharyngeal carcinoma (NPC) is highly prevalent in southern China, especially in Guang Dong and Hong Kong, due to its insidious location of tumorigenesis and various clinical symptoms, most patients has been in locally advanced stage before diagnosed (Lu et al., 2009). Main causes of failure in treatment of high T staged nasopharyngeal carcinoma are residual or recurrence (Dimery et al., 1993; Johnson et al., 2005). Base of skull and poststyloid space are frequent locations where treatment of nasopharyngeal carcinoma fails (Cmelak et al., 2009). When there are extensive invasions of nasopharyngeal carcinoma in base of skull and posterior cranial fossa, in order to avoid excessive radiation dose in brain stem and spinal cord, conventional
منابع مشابه
Preliminary results of a phase I/II study of simultaneous boost irradiation radiotherapy for locally advanced nasopharyngeal carcinoma.
BACKGROUND The purpose of this article is to present preliminary results of simultaneous boost irradiation radiotherapy for locally advanced nasopharyngeal carcinoma (NPC). METHODS Fifty-eight patients who underwent simultaneous boost irradiation radiotherapy for NPC in Cancer Center of Sun Yat-sen University between September 2004 and December 2009 were eligible. Acute and late toxicities we...
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